Article

First clinical validation of whole genome screening on standard trophectoderm biopsies of preimplantation embryos

2022-04-15

Abstract excerpt

Whole Genome Sequencing (WGS) is used in healthcare and in the clinic, with the notable exception of preimplantation genetic testing (PGT). In PGT, only a few cells are available for sequencing, requiring DNA amplification which reduces data quality, sequence fidelity and sharply limits subsequent clinical impact. Here we demonstrate the first clinical validation of WGS on embryo biopsies using our lab development...

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Literature Corpus work: f0568be6-4eef-522b-9559-e35bc374ddd1
DOI: 10.1101/2022.04.14.488421

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