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Clonal evaluation of prostate cancer molecular heterogeneity in biopsy samples by dual immunohistochemistry and dual RNA <i>in situ</i> hybridization

2019-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Prostate cancer is frequently multifocal. Although there may be morphological variation, the genetic underpinnings of each tumor are not clearly understood. To assess the inter and intra tumor molecular heterogeneity in prostate biopsy samples, we developed a combined immunohistochemistry and RNA in situ hybridization method for the simultaneous evaluation of ERG, SPINK1, ETV1 , and ETV4 . Scr...

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Literature Corpus work
865df57e-7d01-5b05-87ec-cec6cc7de0ca
DOI
10.1101/818880
Open publication

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Clonal evaluation of prostate cancer molecular heterogeneity in biopsy samples by dual immunohistochemistry and dual RNA <i>in situ</i> hybridizationDOI 10.1101/818880
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