Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intratumoral heterogeneity and genetic characteristics of prostate cancer.

International journal of cancer - 15 Jun 2020

Wu Bo, Lu Xin, Shen Haibo, Yuan Xiaobin, Wang Xin, Yin Nan, Sun Libin, Shen Pengliang, Hu Caoyang, Jiang Huanrong, Wang Dongwen

Abstract excerpt

Prostate cancer is a heterogeneous disease and optimum gene targeting treatment is often impermissible. We aim to determine the intratumoral genomic heterogeneity of prostate cancer and explore candidate genes for targeted therapy. Exome sequencing was performed on 37 samples from 16 patients with prostate cancer. Somatic variant analysis, copy number variant (CNV) analysis, clonal evolution analysis and variant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Autophagy-Related Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clonal Evolution

Share to Genetic Heterogeneity

Share to Prostate

Share to Prostatectomy

Share to ras-GRF1

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 32159858
DOI: 10.1002/ijc.32961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intratumoral heterogeneity and genetic characteristics of prostate cancer.PMID 32159858Read ↗

Molecular Pathology of Prostate Cancer.Semantic proximity Read ↗

Translational and clinical implications of the genetic landscape of prostate cancer.Semantic proximity Read ↗

Clinical variability and molecular heterogeneity in prostate cancerSemantic proximity Read ↗

The complexity of prostate cancer: genomic alterations and heterogeneity.Semantic proximity Read ↗

Regional biases in mutation screening due to intratumoural heterogeneity of prostate cancer.Semantic proximity Read ↗

Spatial Intratumor Genomic Heterogeneity within Localized Prostate Cancer Revealed by Single-nucleus Sequencing.Semantic proximity Read ↗

Future directions for precision oncology in prostate cancerSemantic proximity Read ↗

Biomarkers Associated with Tumor Heterogeneity in Prostate CancerSemantic proximity Read ↗

Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic PrognosticatorsSemantic proximity Read ↗

The diverse heterogeneity of molecular alterations in prostate cancer identified through next-generation sequencing.Semantic proximity Read ↗

Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity.Semantic proximity Read ↗

Genomic, pathological, and clinical heterogeneity as drivers of personalized medicine in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.