Article

A systematic genetic analysis and visualization of phenotypic heterogeneity among orofacial cleft GWAS signals

2018-05-28

Abstract excerpt

Phenotypic heterogeneity is a hallmark of complex traits, and genetic studies of such traits may focus on them as a single diagnostic entity or by analyzing specific components. For example, in orofacial clefting (OFC), three subtypes – cleft lip (CL), cleft lip and palate (CLP), and cleft palate (CP) have been studied separately and in combination. To further dissect the genetic architecture of OFCs and how a giv...

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Literature Corpus work: 8648988e-5f6f-51a8-b2a2-ec3627f8342a
DOI: 10.1101/332270

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