Article

IL-21 Signaling in Immunity

2016-02-26

Abstract excerpt

IL-21 is a type I cytokine produced by T cells and natural killer T cells that has pleiotropic actions on a wide range of immune and non-immune cell types. Since its discovery in 2000, extensive studies on the biological actions of IL-21 have been performed in vitro and in vivo . Recent reports describing patients with primary immunodeficiency caused by mutations of IL21 or IL21R have further deepened our know...

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Literature Corpus work: 86338959-6a54-5b05-badd-98115c76e492
DOI: 10.12688/f1000research.7634.1

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