Article

Neutrophil-neuronal crosstalk drives arthritis-induced pain

2025-12-27

Abstract excerpt

Pain in rheumatoid arthritis (RA) often persists despite effective control of inflammation, suggesting distinct mechanisms driving nociception. In both patients and animal models, pain severity does not strongly correlate with the degree of inflammation 1,2 . Sensory neurons, with cell bodies located in the dorsal root ganglia (DRG), innervate peripheral tissues, including joints, and transmit pain signals to the...

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Literature Corpus work: 861a8ab3-9251-5124-a168-a0b494c08d45
DOI: 10.64898/2025.12.27.696652

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