Article

Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis

2022-05-07

Abstract excerpt

<h4>Background</h4> It remains unknown why ∼30% of patients with psychotic disorders fail to respond to treatment. Previous genomic investigations into treatment-resistant psychosis have been inconclusive, but some evidence suggests a possible link between rare disease-associated copy number variants (CNVs) and worse clinical outcomes in schizophrenia. Here, we test whether schizophrenia-associated CNVs are more p...

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Literature Corpus work: 8614dcd0-583a-5133-898a-91854c57305c
DOI: 10.1101/2022.05.04.22274673

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