Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A review of antipsychotic therapy effectiveness and tolerability among individuals with copy number variants relevant to schizophrenia.

Psychiatric genetics - 1 Jun 2025

Colijn Mark A

Abstract excerpt

Although numerous copy number variants (CNVs) are considered pathogenic with respect to the development of schizophrenia, only eight loci have reached genome-wide significance. Reviews/studies characterizing antipsychotic use in this context exist for only three corresponding CNV syndromes. As these disorders also predispose to neurodevelopmental anomalies and various medical comorbidities, affected individuals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Chromosome Deletion
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NRXN1 gene

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Schizophrenia

Share to Treatment Outcome

Source

Identifiers

PMID: 40145886
DOI: 10.1097/YPG.0000000000000392

Genes

NRXN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A review of antipsychotic therapy effectiveness and tolerability among individuals with copy number variants relevant to schizophrenia.PMID 40145886Read ↗

Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for Schizophrenia.Semantic proximity Read ↗

Copy Number Variations and Schizophrenia.Semantic proximity Read ↗

Copy Number Variations in Schizophrenia: Critical Review and New Perspectives on Concepts of Genetics and DiseaseSemantic proximity Read ↗

Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis.Semantic proximity Read ↗

Genomic copy number variations: A breakthrough in our knowledge on schizophrenia etiology?Semantic proximity Read ↗

Copy number variation and schizophrenia.Semantic proximity Read ↗

Copy Number Variations in Neuropsychiatric Disorders.Semantic proximity Read ↗

Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant PsychosisSemantic proximity Read ↗

Copy number variant syndromes are frequent in schizophrenia: progressing towards a CNV-schizophrenia modelSemantic proximity Read ↗

Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients.Semantic proximity Read ↗

Rare chromosomal deletions and duplications increase risk of schizophrenia.Semantic proximity Read ↗

The role of DNA copy number variation in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.