Article

Identification of differentially methylated cell-types in Epigenome-Wide Association Studies

2018-09-20

Abstract excerpt

An outstanding challenge of Epigenome-Wide Association Studies (EWAS) performed in complex tissues is the identification of the specific cell-type(s) responsible for the observed differential DNA methylation. Here, we present a novel statistical algorithm, called CellDMC, which is able to identify not only differentially methylated positions, but also the specific cell-type(s) driving the differential methylation....

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Literature Corpus work: 85fd008f-3201-5f73-b2df-5eaa38855dde
DOI: 10.1101/421966

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