Article

RadD from <i>Fusobacterium nucleatum</i> Engages NKp46 to Promote Antitumor Cytotoxicity

2025-07-31

Abstract excerpt

Fusobacterium nucleatum , a Gram-negative bacterium implicated in periodontal disease, has emerged as a contributor to tumor progression in various cancers. Whether the presence of Fusobacterium nucleatum inhibits tumor progression is largely unknown. Here, we identify a subspecies-specific interaction between F. nucleatum and the natural killer (NK) cell receptor NKp46. Analysis of TCGA datasets revealed that t...

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Literature Corpus work: 85f77b9c-e32b-532e-8d73-2ff76aa8b3a6
DOI: 10.1101/2025.07.26.666929

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