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Modulation of the Host Cell Transcriptome and Epigenome by Fusobacterium nucleatum

26 Oct 2021

Abstract excerpt

Fusobacterium nucleatum is a bacterium normally found in the healthy oral cavity but also has an emerging role in colorectal cancer and other cancer settings. The host-microbe interactions of F. nucleatum and its involvement in tumor initiation, progression, and treatment resistance are not fully understood. We explored host cell changes that occur in response to F. nucleatum. We identified key genes...

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PMID: 34700376
DOI: 10.1128/mbio.02062-21

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