Article

Antigen expression and host-parasite interactions of Plasmodium falciparum infections in Malawian paediatric patients

2013-01-01

Abstract excerpt

Introduction: The process of sequestration involving specific cytoadhesion between parasite ligands expressed on the surface of the parasitised red blood cells (pRBC) and host vascular endothelium contributes to pathogenesis of severe falciparum malaria. A major polymorphic surface antigen implicated in cytoadhesion is the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 is encoded by the var...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 85aec768-f7d7-5d6c-9072-0820857db944
DOI: 10.17638/00011453

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antigen expression and host-parasite interactions of Plasmodium falciparum infections in Malawian paediatric patientsDOI 10.17638/00011453Read

Parasite adhesion and immune evasion in placental malaria.Semantic proximity Read

Malaria's deadly grip: cytoadhesion of Plasmodium falciparum -infected erythrocytesSemantic proximity Read

VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental MalariaSemantic proximity Read

Molecular Principles of Intrauterine Growth Restriction in Plasmodium Falciparum InfectionSemantic proximity Read

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposureSemantic proximity Read

Effect of red blood cell variants on childhood malaria in Mali: a prospective cohort study.Semantic proximity Read

Expression of specific <i>var</i> gene subtypes is differentially associated with severe malaria syndromesSemantic proximity Read

Variable surface antigen expression, virulence, and persistent infection by Plasmodium falciparum malaria parasitesSemantic proximity Read

Meta-analysis of Plasmodium falciparum var Signatures Contributing to Severe Malaria in African Children and Indian Adults.Semantic proximity Read

Plasmodium falciparum infected erythrocyte induced modulation of host endothelial cellsSemantic proximity Read

Knobs, Adhesion, and Severe Falciparum MalariaSemantic proximity Read

PfEMP1-DBL1α amino acid motifs in severe disease states of <i>Plasmodium falciparum</i> malariaSemantic proximity Read