Article

Targeting To Hedgehog Signalling Pathway Increase Sensitivity Anticancer Effects of Arsenic Trioxide Mediated By miR-326

2021-04-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The radical cure of Glioblastoma multiforme (GBM) is a troublesome medical problem, owing to its resistance to temozolomide chemotherapy and very poor surgical results or high relapse rate. Resistance to temozolomide emerges from numerous signalling pathways that are altered in GBM, especially the hedgehog signalling pathway. Hence, further research is urgent ne...

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Literature Corpus work: 859e0f4f-63d2-557b-b094-bf3d703477f9
DOI: 10.21203/rs.3.rs-340883/v1

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