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Article

Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk.

Journal of lipid research - 1 Aug 2018

Minchin James E N, Scahill Catherine M, Staudt Nicole, Busch-Nentwich Elisabeth M, Rawls John F

Abstract excerpt

The regional distribution of adipose tissues is implicated in a wide range of diseases. For example, proportional increases in visceral adipose tissue increase the risk for insulin resistance, diabetes, and CVD. Zebrafish offer a tractable model system by which to obtain unbiased and quantitative phenotypic information on regional adiposity, and deep phenotyping can explore complex disease-related adiposity...

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Identifiers

PMID: 29794036
DOI: 10.1194/jlr.D084525
PMCID: PMC6071777

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