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The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)

18 Mar 2016

Abstract excerpt

During development of disease, complex intracellular signaling pathways regulate an intricate series of events, including resistance to external toxins, the secretion of cytokines and the production of pathological phenomena. Adenosine 3',5'-cyclic monophosphate (cAMP) is a nucleotide that acts as a key second messenger in numerous signal transduction pathways. cAMP regulates various cellular functions, including...

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PMID: 27035868
DOI: 10.3892/mmr.2016.5005

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