Article

Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

2020-06-16

Abstract excerpt

Emerging data indicate that complement and neutrophils are involved in the maladaptive host immune response that fuels hyper-inflammation and thrombotic microangiopathy increasing the mortality rate in coronavirus disease 2019 (COVID-19). Here, we investigated the interaction between complement and the platelet/neutrophil extracellular traps (NETs)/thrombin axis, using COVID-19 clinical samples, cell-based inhibit...

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Identifiers and source

Literature Corpus work: 8557ee0b-6e48-5808-98cf-1e686c21154f
DOI: 10.1101/2020.06.15.20131029

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