Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.

doi:10.1161/CIRCULATIONAHA.120.048488

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Article

Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.

Circulation - 22 Sept 2020

Nicolai Leo, Leunig Alexander, Brambs Sophia, Kaiser Rainer, Weinberger Tobias, Weigand Michael, Muenchhoff Maximilian, Hellmuth Johannes C, Ledderose Stephan, Schulz Heiko, Scherer Clemens, Rudelius Martina, Zoller Michael, Höchter Dominik, Keppler Oliver, Teupser Daniel, Zwißler Bernhard, von Bergwelt-Baildon Michael, Kääb Stefan, Massberg Steffen, Pekayvaz Kami, Stark Konstantin

Abstract excerpt

BACKGROUND: Severe acute respiratory syndrome corona virus 2 infection causes severe pneumonia (coronavirus disease 2019 [COVID-19]), but the mechanisms of subsequent respiratory failure and complicating renal and myocardial involvement are poorly understood. In addition, a systemic prothrombotic phenotype has been reported in patients with COVID-19. METHODS: A total of 62 subjects were included in our study...

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PMID: 32755393
DOI: 10.1161/CIRCULATIONAHA.120.048488
PMCID: PMC7497892

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