Article

Associations of Genetic Liability to Six Psychiatric Disorders With Cardiometabolic Diseases

2025-03-12

Abstract excerpt

<h4>IMPORTANCE</h4> Individuals with psychiatric disorders have increased risk of cardiometabolic diseases (CMDs). Evaluating how psychiatric genetic liability relates to CMD may clarify mechanisms. <h4>OBJECTIVE</h4> Identify genetic overlap between psychiatric disorders and CMDs independent of cross-disorder pleiotropy, BMI, and smoking. <h4>DESIGN, SETTING, AND PARTICIPANTS</h4> Three Northern European cohor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 853862a0-1628-5f3a-b8da-1fd1b5d9bbc0
DOI: 10.1101/2025.03.11.25323757

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Associations of Genetic Liability to Six Psychiatric Disorders With Cardiometabolic DiseasesDOI 10.1101/2025.03.11.25323757Read

Quantifying the Relative Importance of Genetics and Environment on the Comorbidity between Mental- and Cardiometabolic Disorders: A Comprehensive Analysis of National Register Data from 17 million ScandinaviansSemantic proximity Read

Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million ScandinaviansSemantic proximity Read

Phenotypic Associations and Shared Genetic Etiology between Bipolar Disorder and Cardiometabolic TraitsSemantic proximity Read

Divergent patterns of genetic overlap between severe mental disorders and metabolic markersSemantic proximity Read

Uncovering the genetic underpinnings for different psychiatric disorder combinations.Semantic proximity Read

Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record dataSemantic proximity Read

Uncovering the genetic underpinnings for different psychiatric disorder combinationsSemantic proximity Read

Familial coaggregation and shared genetic loading of mental disorders and cardiovascular diseases.Semantic proximity Read

Sex differences in shared genetic determinants between severe mental disorders and metabolic traits.Semantic proximity Read

Genetic susceptibility of cardiometabolic outcomes in schizophrenia spectrum disorders.Semantic proximity Read

Inference of causal relationships based on the genetics of cardiometabolic traits and conditions unique to females in >50,000 participantsSemantic proximity Read

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individualsSemantic proximity Read