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Interplay of Oxidative Stress, Autophagy, and Rubicon in Ovarian Follicle Dynamics: Orchestrating Ovarian Aging

2025-07-04

Abstract excerpt

Organ functions generally decline with age, but the ovary is a prototypical organ that undergoes functional loss over time. Autophagy plays a crucial role in maintaining organ homeostasis, and age-related upregulation of the autophagy inhibitor protein, Rubicon, has been linked to cellular and tissue dysfunction. This review describes how granulosa cell autophagy supports follicular growth and oocyte selection and...

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Literature Corpus work
8534e98a-d090-5acf-9f21-bb7e0ffbd960
DOI
10.20944/preprints202507.0406.v1
Open publication

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Interplay of Oxidative Stress, Autophagy, and Rubicon in Ovarian Follicle Dynamics: Orchestrating Ovarian AgingDOI 10.20944/preprints202507.0406.v1
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