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Article

Autophagy in Female Fertility: A Role in Oxidative Stress and Aging

31 Dec 2019

Abstract excerpt

Significance: The precipitous age-related decline in female fertility is intimately associated with a reduction in both the quantity and quality of the germline (oocytes). Although complex etiologies undoubtedly contribute to the deterioration of oocyte quality, increasing attention has focused on the pervasive impact of oxidative stress. Indeed, the prolonged lifespan of the meiotically arrested oocyte places...

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PMID: 31892284
DOI: 10.1089/ars.2019.7986

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