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Article

Aging and oocyte competence: A molecular cell perspective

29 May 2023

Abstract excerpt

Follicular microenvironment is paramount in the acquisition of oocyte competence, which is dependent on two interconnected and interdependent processes: nuclear and cytoplasmic maturation. Extensive research conducted in human and model systems has provided evidence that those processes are disturbed with female aging. In fact, advanced maternal age (AMA) is associated with a lower chance of pregnancy and live...

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PMID: 37248206
DOI: 10.1002/wsbm.1613

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