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Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse <i>Caenorhabditis</i> nematodes

2024-10-26

Abstract excerpt

Aging is a pan-metazoan process with significant consequences for human health and society—discovery of new compounds that ameliorate the negative health impacts of aging promise to be of tremendous benefit across a number of age-based comorbidities. One method to prioritize a testable subset of the nearly infinite universe of potential compounds is to use computational prediction of their likely anti-aging capaci...

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Literature Corpus work
851cadb3-31c7-5ae9-a5ba-645d19aa82b2
DOI
10.1101/2024.10.23.619838
Open publication

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Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse <i>Caenorhabditis</i> nematodesDOI 10.1101/2024.10.23.619838
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