Article

Imipenem Resistance: A Clarion Call to Antibiotic Stewardship

2026-05-28

Abstract excerpt

<title>Abstract</title> <p> Background Imipenem, <bold>a carbapenem antibiotic</bold> with a broader antimicrobial spectrum and greater potency than other beta-lactam antibiotics, has been considered a last-resort antibiotic for severe Gram-negative infections. However, escalating resistance now threatens its clinical utility worldwide. This review synthesizes current knowledge on the epidemiology, molecular...

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Literature Corpus work: ff31a523-7c9d-550e-868e-13423b04f16d
DOI: 10.21203/rs.3.rs-9832011/v1

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