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Regulation of the Activity of the Dual Leucine Zipper Kinase by Distinct Mechanisms

2024-01-04

Abstract excerpt

The dual leucine zipper kinase (DLK) alias mitogen-activated protein 3 kinase 12 (MAP3K12) has gained much attention in recent years. DLK belongs to the mixed lineage kinases, characterized by homology to serine/threonine and tyrosine kinase but exerts serine/threonine kinase activity. DLK has been implicated in many diseases including several neurodegenerative diseases, glaucoma, and diabetes mellitus. As a MAP3K...

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Literature Corpus work
84d6da79-c6e1-53c3-b341-4a65797aa23f
DOI
10.20944/preprints202401.0297.v1
Open publication

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Regulation of the Activity of the Dual Leucine Zipper Kinase by Distinct MechanismsDOI 10.20944/preprints202401.0297.v1
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