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Prosaposin: A Multifaceted Protein Orchestrating Biological Processes and Diseases

22 Jul 2025

Abstract excerpt

Prosaposin (PSAP), a multifunctional protein, plays a central role in various biological processes and diseases. It is the precursor of lysosomal activating protein, which is important for lipid metabolism and glucose metabolism. PSAP is implicated in cell signaling, neuroprotection, immunomodulation, and tumorigenesis. In neurological disorders, PSAP acts as a neurotrophic factor influencing nerve cell survival...

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PMID: 40801564
DOI: 10.3390/cells14151131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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