Article
The NDR/LATS protein kinases in immunology and cancer biology.
Seminars in cancer biology - 1 Feb 2018
Sharif Ahmad A D, Hergovich Alexander
Abstract excerpt
The NDR (nuclear Dbf2-related)/LATS (large tumour suppressor) family of kinases represents a subclass of the AGC (protein kinase A (PKA)/PKG/PKC-like) group of serine/threonine protein kinases. Members of the NDR/LATS family are vital components of conserved pathways controlling essential cellular processes, such as proliferation (cell cycle progression) and cell death. In particular, the central involvement of...
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