Article

Confounder-adjusted MRI-based predictors of multiple sclerosis disability

2022-04-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Both aging and multiple sclerosis (MS) cause central nervous system (CNS) atrophy. Excess brain atrophy in MS has been interpreted as accelerated aging. Current paper tests an alternative hypothesis: MS causes CNS atrophy by mechanism(s) different from physiological aging. Thus, subtracting effects of physiological confounders on CNS structures would isolate MS-specific effe...

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Literature Corpus work: 848262d3-629e-5188-9c4c-62c17fb11468
DOI: 10.1101/2022.04.18.22273974

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