Article

Defining multiple sclerosis subtypes using machine learning

2019-12-04

Abstract excerpt

Multiple sclerosis (MS) is subdivided into four phenotypes on the basis of medical history and clinical symptoms. These phenotypes are defined retrospectively and lack clear pathobiological underpinning. Since Magnetic Resonance Imaging (MRI) better reflects disease pathology than clinical symptoms, we aimed to explore MRI-driven subtypes of MS based on pathological changes visible on MRI using unsupervised machin...

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Literature Corpus work: d21243b2-fbba-5b6d-acbd-7e74b61e0964
DOI: 10.1101/19011080

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