Article

Effect of rapamycin on mitochondria and lysosomes in fibroblasts from patients with mtDNA mutations

2021-04-01

Abstract excerpt

Maintaining mitochondrial function and dynamics is crucial for cellular health. In muscle, defects in mitochondria result in severe myopathies where accumulation of damaged mitochondria causes deterioration and dysfunction. Importantly, understanding the role of mitochondria in disease is a necessity to determine future therapeutics. One of the most common myopathies is m itochondrial e ncephalopathy l actic a...

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Literature Corpus work: 846dfa86-471c-5fdb-92d5-1952e256ff8f
DOI: 10.1101/2021.03.31.437507

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