Effect of rapamycin on mitochondria and lysosomes in fibroblasts from patients with mtDNA mutations.

Abstract excerpt

Maintaining mitochondrial function and dynamics is crucial for cellular health. In muscle, defects in mitochondria result in severe myopathies where accumulation of damaged mitochondria causes deterioration and dysfunction. Importantly, understanding the role of mitochondria in disease is a necessity to determine future therapeutics. One of the most common myopathies is mitochondrial encephalopathy lactic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to MELAS Syndrome
• Share to Membrane Potential, Mitochondrial