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O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis

2024-03-02

Abstract excerpt

Gene transcription is a highly regulated process, and deregulation of transcription factors activity underlies numerous pathologies including cancer. Albeit near four decades of studies have established that the E2F pathway is a core transcriptional network that govern cell division in multi-cellular organisms 1,2 , the molecular mechanisms that underlie the functions of E2F transcription factors remain incomplet...

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Literature Corpus work
844809e6-0571-52f3-bb9f-64d601d510b6
DOI
10.1101/2024.03.01.582838
Open publication

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O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesisDOI 10.1101/2024.03.01.582838
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