Article

Graph Network-Based Analysis of Disease-Gene-Drug Associations: Zero-Shot Disease-Drug Prediction and Analysis Strategies

2024-12-30

Abstract excerpt

Existing drug repurposing methods have key limitations, primarily stemming from their reliance on known direct associations between diseases and drugs for supervised learning, as well as the need for large amounts of prior disease or drug information or feature data. In practice, many disease-drug connections remain unknown, and prior information is often complex and difficult to acquire and organize, limiting the...

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Literature Corpus work: 838000af-1f89-5d25-b214-e0e2d1ade2ce
DOI: 10.1101/2024.12.30.630746

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