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A Literature-Based Knowledge Graph Embedding Method for Identifying Drug Repurposing Opportunities in Rare Diseases

2019-08-07

Abstract excerpt

One in ten people are affected by rare diseases, and three out of ten children with rare diseases will not live past age five. However, the small market size of individual rare diseases, combined with the time and capital requirements of pharmaceutical R&D, have hindered the development of new drugs for these cases. A promising alternative is drug repurposing, whereby existing FDA-approved drugs might be used to t...

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Literature Corpus work
a029b40f-86f2-53c4-a15d-c6aeab0541f4
DOI
10.1101/727925
Open publication

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A Literature-Based Knowledge Graph Embedding Method for Identifying Drug Repurposing Opportunities in Rare DiseasesDOI 10.1101/727925
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