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Article

Personalized characterization of diseases using sample-specific networks

2016-05-24

Abstract excerpt

<h4>ABSTRACT</h4> A complex disease generally results not from malfunction of individual molecules but from dysfunction of the relevant system or network, which dynamically changes with time and conditions. Thus, estimating a condition-specific network from a sample is crucial to elucidating the molecular mechanisms of complex diseases at the system level. However, there is currently no effective way to construct...

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Literature Corpus work
83720348-6a85-5112-a02f-b5f866376280
DOI
10.1101/042838
Open publication

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