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Article

Personalized characterization of diseases using sample-specific networks.

Nucleic acids research - 15 Dec 2016

Liu Xiaoping, Wang Yuetong, Ji Hongbin, Aihara Kazuyuki, Chen Luonan

Abstract excerpt

A complex disease generally results not from malfunction of individual molecules but from dysfunction of the relevant system or network, which dynamically changes with time and conditions. Thus, estimating a condition-specific network from a single sample is crucial to elucidating the molecular mechanisms of complex diseases at the system level. However, there is currently no effective way to construct such an...

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Identifiers

PMID: 27596597
DOI: 10.1093/nar/gkw772
PMCID: PMC5159538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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