Article

A failed top-down control from prefrontal cortex to amygdala in generalized anxiety disorder: evidence from resting-state fMRI with Granger causality analysis

2019-03-12

Abstract excerpt

<h4>Objective</h4> In generalized anxiety disorder (GAD), abnormal top-down control from prefrontal cortex (PFC) to amygdala is a widely accepted hypothesis through which “emotional dysregulation model” may be explained. However, whether and how the PFC directly exerted abnormal top-down control on amygdala remained largely unknown. We aim to investigate the amygdala-based effective connectivity by using Granger...

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Literature Corpus work: 833d2fee-08f6-580f-8a38-d9b15f3aab38
DOI: 10.1101/573634

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