Article

Distinct neurostructural signatures of anxiety-, fear-related and depressive disorders: a comparative voxel-based meta-analysis

2021-11-04

Abstract excerpt

Internalizing disorders encompass anxiety, fear and depressive disorders. While the DSM-5 nosology conceptualizes anxiety and fear-related disorders as an entity, dimensional psychopathology models suggest that generalized anxiety disorders (GAD) and major depression originate from an overarching “anxious-misery” factor whereas fear-related disorders originate from the “fear” factor. Given that a neurobiological e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f2e6d530-a9c8-551f-be8b-46ec5a23cc8f
DOI: 10.1101/2021.11.02.21265836

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct neurostructural signatures of anxiety-, fear-related and depressive disorders: a comparative voxel-based meta-analysisDOI 10.1101/2021.11.02.21265836Read

The neuroanatomical basis for depression, anxiety, rumination, and worry—a systematic review and meta-analysisSemantic proximity Read

The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology.Semantic proximity Read

Brain-Based Classification of Youth with Anxiety Disorders: an ENIGMA-ANXIETY Transdiagnostic Examination using Machine LearningSemantic proximity Read

Resting-state Functional Connectivity in Anxiety Disorders: A Multicenter fMRI StudySemantic proximity Read

Specific amygdala and hippocampal subfield volumes in social anxiety disorder and their relation to clinical characteristics – an international mega-analysisSemantic proximity Read

Anxious brains: A combined data fusion machine learning approach to predict trait anxiety from gray and white matter featuresSemantic proximity Read

Shared and Distinct Brain Regions in Anxiety, Depression, and Neuroticism: A Multi-Phenotypic Approach Using Data from the UK BiobankSemantic proximity Read

Multi-scale neural signatures of major depressive, anxiety, and stress-related disordersSemantic proximity Read

The many faces of anxiety-neurobiological correlates of anxiety phenotypes.Semantic proximity Read

Multimodal phenotypic classification of generalized anxiety and panic using structural MRI data and psychosocial factors: machine learning results from the German National Cohort (NAKO) study.Semantic proximity Read

Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorderSemantic proximity Read

Causal relationship between cortical structural changes and onset of anxiety disorder: evidence from Mendelian randomization.Semantic proximity Read