Article

Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons

2024-07-24

Abstract excerpt

Sensory neurons generated from induced pluripotent stem cells (iSNs) are used to model human peripheral neuropathies, however current differentiation protocols produce sensory neurons with an embryonic phenotype. Peripheral glial cells contact sensory neurons early in development and contribute to formation of the canonical pseudounipolar morphology, but these signals are not encompassed in current iSN differentia...

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Identifiers and source

Literature Corpus work: 832d346b-624a-53de-b32f-3327be617d19
DOI: 10.1101/2024.07.24.604966

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