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Article

Enriched population of PNS neurons derived from human embryonic stem cells as a platform for studying peripheral neuropathies.

PloS one - 18 Feb 2010

Valensi-Kurtz Moran, Lefler Sharon, Cohen Malkiel A, Aharonowiz Michal, Cohen-Kupiec Rachel, Sheinin Anton, Ashery Uri, Reubinoff Benjamin, Weil Miguel

Abstract excerpt

BACKGROUND: The absence of a suitable cellular model is a major obstacle for the study of peripheral neuropathies. Human embryonic stem cells hold the potential to be differentiated into peripheral neurons which makes them a suitable candidate for this purpose. However, so far the potential of hESC to differentiate into derivatives of the peripheral nervous system (PNS) was not investigated enough and in...

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Identifiers

PMID: 20174633
DOI: 10.1371/journal.pone.0009290
PMCID: PMC2823780

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