Article

A Dysbiotic Gut Microbiome Suppresses Antibody Mediated-Protection Against <i>Vibrio cholerae</i>

2019-08-09

Abstract excerpt

Vibrio cholerae is the etiologic agent of cholera, a severe diarrheal disease that represents a significant burden on global health and productivity. Despite the pressing need, available preventative measures such as oral cholera vaccines exhibit highly variable protective efficacy. We hypothesized that one contributor to vaccine efficacy variability across geographical regions may be due to differences in gut mic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 832a22ea-8f4c-5b6c-b945-3d679ceb24e5
DOI: 10.1101/730796

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Dysbiotic Gut Microbiome Suppresses Antibody Mediated-Protection Against <i>Vibrio cholerae</i>DOI 10.1101/730796Read

Members of the human gut microbiota involved in recovery from Vibrio cholerae infectionSemantic proximity Read

Predicting <i>Vibrio cholerae</i> infection and disease severity using metagenomics in a prospective cohort studySemantic proximity Read

Human Gut Microbiota Predicts Susceptibility to Vibrio cholerae InfectionSemantic proximity Read

Increased bacterial taxonomic and functional diversity is associated with impaired rotavirus vaccine immunogenicity in infants from India and MalawiSemantic proximity Read

Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigensSemantic proximity Read

Composition of gut microbiota and its influence on the immunogenicity of oral rotavirus vaccines.Semantic proximity Read

Influence of the intestinal microbiota on the immune response to oral poliovirus and rotavirus vaccines in a low-income community in south IndiaSemantic proximity Read

Interplay Between the Gut Microbiome and Typhoid Fever: Insights from Endemic Countries and a Controlled Human Infection ModelSemantic proximity Read

Minimal Variations of Oral Virome and Microbiome in Human IgA DeficiencySemantic proximity Read

The emerging role of the gut microbiota in vaccination responsesSemantic proximity Read

Pharmacomicrobiomics of mRNA Vaccines: Gut Microbiota–Driven Modulation of Vaccine PharmacodynamicsSemantic proximity Read

Human antibody targeting Vibrio cholerae O1 O-specific polysaccharide induces an amotile hypovirulent bacterial phenotype: mechanism of protection against cholera.Semantic proximity Read