Article

Pharmacomicrobiomics of mRNA Vaccines: Gut Microbiota–Driven Modulation of Vaccine Pharmacodynamics

2025-09-24

Abstract excerpt

Messenger RNA (mRNA) vaccines represent a significant leap in vaccinology, yet individual immune responses to them are highly variable. Emerging evidence identifies the gut microbiota as a critical modulator of vaccine efficacy. It synthesizes the mechanisms by which gut microbes influence the pharmacodynamics of mRNA vaccines. The gut microbiota regulates host immunity through pathways essential for vaccine respo...

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Literature Corpus work: 77a60502-2de4-50a8-b43e-8d89e582e9fe
DOI: 10.22541/au.175868682.25472537/v1

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