Article

Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens

2021-12-01

Abstract excerpt

The degree of protection conferred after receiving an oral cholera vaccine (OCV) varies based on age, prior exposure to Vibrio cholerae , and unknown factors. Recent evidence suggests that the microbiota may mediate some of the unexplained differences in oral vaccine responses. We used metagenomic sequencing of the microbiota at the time of vaccination, and then related microbial features to immune responses afte...

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Literature Corpus work: 9b6487f5-4a5d-58cc-9aa5-19674c3ab0e9
DOI: 10.1101/2021.12.01.470820

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