Article
Composition of gut microbiota and its influence on the immunogenicity of oral rotavirus vaccines.
Vaccine - 7 Jun 2018
Magwira Cliff A, Taylor Maureen B
Abstract excerpt
The introduction of oral rotavirus vaccines (ORVVs) has led to a reduction in number of hospitalisations and deaths due to rotavirus (RV) infection. However, the efficacy of the vaccines has been varied with low-income countries showing significantly lower efficacy as compared to high-income countries. The reasons for the disparity are not fully understood but are thought to be multi-factorial. In this review...
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