Article

A Novel congenic Mouse Model to study Obesity, Diabetes and NAFLD

2022-02-10

Abstract excerpt

The genetic background of the mutant mouse strain plays an important role in disease development. We investigated whether Lepr mutation on different genetic background (WSB/EiJ) influences the development of obesity, diabetes and non-alcoholic fatty liver diseases (NAFLD). For this study heterozygote ( db /+) mice were backcrossed with WSB/EiJ strain (that is resistant to obesity and NAFLD) for more than 10 gene...

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Literature Corpus work: 83063eba-a45b-5ce2-a745-03aba65423f5
DOI: 10.1101/2022.02.08.479645

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