Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Membrane-Tethered Delta-Like 1 Homolog (DLK1) Restricts Adipose Tissue Size by Inhibiting Preadipocyte Proliferation

14 Aug 2012

Abstract excerpt

Adipocyte renewal from preadipocytes has been shown to occur throughout life and to contribute to obesity, yet very little is known about the molecular circuits that control preadipocyte expansion. The soluble form of the preadipocyte factor (also known as pref-1) delta-like 1 homolog (DLK1(S)) is known to inhibit adipogenic differentiation; however, the impact of DLK1 isoforms on preadipocyte proliferation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22891218
DOI: 10.2337/db12-0176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Membrane-Tethered Delta-Like 1 Homolog (DLK1) Restricts Adipose Tissue Size by Inhibiting Preadipocyte ProliferationPMID 22891218Read ↗

Pref-1, a Preadipocyte Secreted Factor That Inhibits AdipogenesisSemantic proximity Read ↗

Adipocyte transdifferentiation and its molecular targetsSemantic proximity Read ↗

Molecular regulation of adipocyte differentiationSemantic proximity Read ↗

From Preadipocyte to Adipocyte: Differentiation-Directed Signals of Insulin from the Cell Surface to the NucleusSemantic proximity Read ↗

Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity.Semantic proximity Read ↗

The Role of Pref-1 during Adipogenic Differentiation: An Overview of Suggested MechanismsSemantic proximity Read ↗

Dual role of delta-like 1 homolog (DLK1) in skeletal muscle development and adult muscle regeneration.Semantic proximity Read ↗

PPARG governs adipogenic differentiation and cell state plasticity in well-differentiated and dedifferentiated liposarcomaSemantic proximity Read ↗

Role of the POZ Zinc Finger Transcription Factor FBI-1 in Human and Murine AdipogenesisSemantic proximity Read ↗

The MLR COMPASS-like complex is required to regulate triglyceride depletion and stress response in the Drosophila fat bodySemantic proximity Read ↗

PPARG governs adipogenic differentiation and cell state plasticity in well-differentiated and dedifferentiated liposarcomaSemantic proximity Read ↗

Deletion of CD44 promotes adipogenesis by regulating PPARɣ and cell cycle-related pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.