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Article

Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells

31 Mar 2016

Abstract excerpt

The stemness maintenance of adipose-derived stem cells (ADSCs) is important for adipose homeostasis and energy balance. Programmed cell death 4 (Pdcd4) has been demonstrated to be involved in the development of obesity, but its possible roles in ADSC function and adipogenic capacity remain unclear. In this study, we demonstrate that Pdcd4 is a key controller that limits the self-renewal and white-to-beige...

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PMID: 27031966
DOI: 10.1038/cddis.2016.75

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