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Proteins differentially expressed between pathogenic and non-pathogenic <i>Entamoeba histolytica</i> clones influence pathogenicity by different mechanisms

2023-06-29

Abstract excerpt

Recently, two genes involved in pathogenicity in a mouse model of amoebic liver abscess were identified based on their differential expression between non-pathogenic (A1 np ) and pathogenic (B2 p ) clones of the Entamoeba histolytica isolate HM:1-IMSS. While overexpression of a gene encoding the metallopeptidase EhMP8-2 decreases the virulence of the pathogenic clone B2 p , overexpression of the gene ehi_1276...

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Literature Corpus work
82ed81d6-78b6-5ad0-880d-110b02d30bf3
DOI
10.1101/2023.06.29.547007
Open publication

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Proteins differentially expressed between pathogenic and non-pathogenic <i>Entamoeba histolytica</i> clones influence pathogenicity by different mechanismsDOI 10.1101/2023.06.29.547007
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