Article

Dual Role of Entamoeba histolytica KERP2 in Regulating Gene Expression and Modulating Host Cell Function for Intestinal Colonization

2025-04-28

Abstract excerpt

<title>Abstract</title> <italic>Entamoeba histolytica</italic> , the protozoan parasite responsible for amoebiasis, deploys a complex array of virulence factors to establish infection and evade host defenses. Here, we identify KERP2 as a dual-function effector that regulates both parasite homeostasis and host cell remodeling. Bioinformatic analyses, cellular localization assays, and functional studies show...

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Literature Corpus work: 6cb65c11-9140-5d82-9cc1-9ec2966d171a
DOI: 10.21203/rs.3.rs-6191032/v1

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