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Article

Transcriptional Silencing of Multiple Genes in Trophozoites of Entamoeba histolytica

22 May 2006

Abstract excerpt

In a previous work we described the transcriptional silencing of the amoebapore A (AP-A) gene (Ehap-a) of Entamoeba histolytica strain HM-1:IMSS. The silencing occurred following transfection with a plasmid containing a 5' upstream region (473 bp) of Ehap-a that included a truncated segment (140 bp) of a short interspersed nuclear element (SINE1). Silencing remained in effect even after removal of the plasmid...

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PMID: 16733544
DOI: 10.1371/journal.ppat.0020048

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