Article

Shared lipidome and proteome signatures of frontotemporal lobar degeneration and Alzheimer’s disease

2026-07-23

Abstract excerpt

<title>Abstract</title> <p>Frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD) differ in their clinical features and genetic etiologies but share progressive cognitive decline. Emerging evidence implicates lipid dysregulation in neurodegeneration, but its extent across FTLD subtypes and how it compares to AD are unclear. Here, we performed integrated lipidomic and proteomic analyses of matched f...

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Literature Corpus work: 82e3d232-0c51-5ef4-b79b-c101e98fad8a
DOI: 10.21203/rs.3.rs-10305293/v1

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